Non-Full-Thickness Macular Holes: A Closer Look

Abstract

Lamellar macular holes and macular pseudoholes are non-full-thickness defects of retinal tissue involving the anatomic fovea, thereby affecting central visual acuity. Non-full-thickness macular holes have been associated with myriad ocular conditions. Originally, lamellar macular holes were described as secondary to diabetic macular edema and macular pseudoholes as idiopathic. The pathogenesis of secondary non-full-thickness macular defects was recently confirmed by spectral-domain optical coherence tomography. These may be mistaken for macular hole lesions, despite careful clinical examination. Careful biomicroscopic examination with a contact lens and optical coherence tomography help to ensure accurate diagnosis. Surgical management with or without air or gas tamponade improves visual acuity and foveal morphology in most eyes.