Abstract
The synthesis, identification and evaluation of the biological activity of a new non-covalent conjugate based on graphene oxide and (5-{[4,6-di(aziridin-1-yl)-1,3,5-triazin-2-yl]-amino}-2,2-dimethyl-1,3-dioxan-5-yl)methyl (5-phenyl-2H-tetrazol-2-yl)acetate were carried out. It was shown that the synthesized nanoconjugate is hemocompatible over the entire studied concentration range (10–100 μm) and demonstrates antiradical activity under irradiation. In addition, the conjugate exhibits cytotoxicity against A549 and HeLa cell lines with IC50 values of 4.0 and 73.7 μm, respectively.
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