Abstract
Prevotella multisaccharivorax Sakamoto et al. 2005 is a species of the large genus Prevotella, which belongs to the family Prevotellaceae. The species is of medical interest because its members are able to cause diseases in the human oral cavity such as periodontitis, root caries and others. Although 77 Prevotella genomes have already been sequenced or are targeted for sequencing, this is only the second completed genome sequence of a type strain of a species within the genus Prevotella to be published. The 3,388,644 bp long genome is assembled in three non-contiguous contigs, harbors 2,876 protein-coding and 75 RNA genes and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
Highlights
Strain PPPA20T (= DSM 17128 = JCM 12954) is the type strain of Prevotella multisaccharivorax [1]
The one yielding the highest score was Prevotella ruminicola (AF218618), which corresponded to an identity of 91.5% and an HSP coverage of 66.3%. (Note that the Greengenes database uses the INSDC (= EMBL/National Center for Biotechnology Information (NCBI)/DDBJ) annotation, which is not an authoritative source for nomenclature or classification.) The highest-scoring environmental sequence was AY550995 ('human carious dentine clone IDRCEC-0032'), which showed an identity of 99.8% and an HSP coverage of 94.5%
The most frequently occurring keywords within the labels of environmental samples which yielded hits of a higher score than the highest scoring species were 'fece' (7.9%), 'goeldi, marmoset' (4.8%), 'microbiom' (4.3%), 'aspect, canal, oral, root' (3.9%) and 'rumen' (3.8%) (54 hits in total). While some of these keywords correspond to the well known habitat of P. multisaccharivorax, others indicate additional habitats related to animals
Summary
There are about 50 species placed in the genus Prevotella [1]. P. multisaccharivorax strain PPPA20T is considered to be an opportunistic pathogen and was isolated from subgingival plaque from a patient with chronic periodontitis. Five more strains isolated from the human oral cavity were placed in the species P. multisaccharivorax [2]. Using non-culture techniques on sites affected by endodontic and periodontal diseases, a large number of sequences have been found that belong to Prevotella and Prevotella-like bacteria. Many of those species have never been isolated or described [3]. We present a summary classification and a set of features for P. multisaccharivorax PPPA20T, together with the description of the non-contiguous finished genomic sequencing and annotation
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