Abstract
Dermatoscopes are routinely used in skin cancer screening but are rarely employed for the diagnosis of other skin conditions. Broader application is promising from a diagnostic point of view as biopsies for differential diagnosis may be avoided but it requires non-contact devices allowing a comparably large field of view that are not commercially available today. Autofocus and color reproducibility are specific challenges for the development of dermatoscopy for application beyond cancer screening. We present a prototype for such a system including solutions for autofocus and color reproducibility independent of ambient lighting. System performance includes sufficiently high feature resolution of up to 30 µm and feature size scaling fulfilling the requirements to apply the device in regular skin cancer screening.
Highlights
A dermatoscope is the standard instrument for a first examination of skin conditions
Relevant camera parameters were measured with and without liquid lens included in the setup to Relevant cameraperformance, parameters were measured and without lens included the setup compare the system i.e., focal length,with resolution, depthliquid of field (DOF), and in image scale to compare the system performance, i.e., focal length, resolution, depth of field (DOF), and image
The non-contact dermatoscope presented in this work features both an integrated autofocus function calibrated by using an infrared laser-based distance sensor as well as image post-processing
Summary
A dermatoscope is the standard instrument for a first examination of skin conditions. State-of-the-art dermatoscopy devices today are mostly contact based and often include a camera to capture digital images for documentation. Compared to a non-contact setup, a contact-based dermatoscope exhibits several disadvantages. State of the art contact-based dermatoscopes have built-in cameras to make the pictures digitally available. The skin contact may cause distortion of the skin geometry, which makes it more difficult to compare pictures made at different examinations. When thinking of infected lesions, the contact can be painful and represents a larger invasion to the privacy of patients. A non-contact device circumvents all these problems. Challenges of a non-contact design are the implementation of a variable focus and the realization of a lighting situation, which is independent from the surrounding light
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