Abstract
Non-coding small RNA mainly includes microRNA, small interfering RNA and RNA interacting with PIWI protein. Studies have shown that non-coding small RNA plays an increasingly important role in the epigenetic regulation. Non-coding small RNA is involved in the regulation of gene expression by gene transcription, post-transcription and mRNA translation. Non-coding small RNA is closely related to many human diseases, especially the diagnosis, treatment and prognosis of melanoma. Key words: Melanoma; Non-coding small RNA
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