Abstract

Non — alcoholic steatohepatitis is a syndrome that develops in patients who do not abuse alcohol, while the nature of liver damage is histologically indistinguishable from alcoholic hepatitis. The condition occurs as a result of excessive accumulation of fats (triglycerides) in the liver, determined by the results of instrumental research methods or histology. Currently, non — alcoholic steatohepatitis (non-alcoholic fatty liver disease, NAFLD) is the most common chronic disease of the biliary system in developed countries and affects from 25 to 30 % of the adult population. The total prevalence in the world is 25.24 %. In the Russian Federation, according to recent studies, NAFLD was approximately 38.3 % in outpatient patients. NAFLD is closely associated with obesity, especially abdominal, which significantly increases cardiometabolic risk and affects morbidity, life expectancy and prognosis of patients. In obese patients, the prevalence of various forms of non-alcoholic fatty liver disease is significantly higher than in non-obese individuals.

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