Abstract

Introduction:Hemodialysis (HD) is a complex therapy that imposes several changes in the patient's life. Failure to follow therapy recommendations is called non-adherence (NA). The patient's illness perception, severity of chronic kidney disease, and individual strategies for coping with HD can have an impact on NA to the demands of therapy.Methods:This was a cross-sectional study with end-stage renal disease patients on conventional HD in Salvador, Bahia. We evaluated attendance to treatment and interdialytic weight gain (IDWG) as parameters of NA to HD, and investigated its association with clinical aspects and measures of disease perception (illness effects questionnaire - IEQ) and severity of nephropathy (end stage renal disease severity index - ESRD-SI), by analyzing Pearson or Spearman correlation.Results:79 patients were evaluated, 57% male, aged 53.1 ± 12.3 years, with length of HD of 108 (89 - 131.5) months. Age correlated with ESRD-SI (r = 0.43) and NA parameters: negative correlation with relative IDWG (r = -0.41) and reduction in sessions (r = -0.31) and positive correlation with %HD performed (r = 0.25). The scores on the IEQ and ESRD-SI showed a positive correlation (r = 0.44; p <0.001), but did not show any correlation with the analyzed NA parameters.Conclusions:We did not find a correlation between illness perception and severity index of advanced nephropathy with the behaviors of NA to chronic HD. In this study, age correlated both with the perception of severity of advanced nephropathy and the parameters of NA to chronic HD.

Highlights

  • Hemodialysis (HD) is a complex therapy that imposes several changes in the patient's life

  • Chronic hemodialysis (HD) treatment in end-stage renal disease (ESRD) causes important changes in the patient’s life, who is susceptible to a pathology with multiple implications in daily life and life expectancy[1]

  • We previously identified a stability of the behavior of NA to HD in a cohort through repeated assessments with an interval of 6 years, favoring the hypothesis that patients present behavioral patterns when faced with the demands of renal-replacement therapy (RRT)[8]

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Summary

Introduction

Hemodialysis (HD) is a complex therapy that imposes several changes in the patient's life. The patient's illness perception, severity of chronic kidney disease, and individual strategies for coping with HD can have an impact on NA to the demands of therapy. We evaluated attendance to treatment and interdialytic weight gain (IDWG) as parameters of NA to HD, and investigated its association with clinical aspects and measures of disease perception (illness effects questionnaire - IEQ) and severity of nephropathy (end stage renal disease severity index - ESRD-SI), by analyzing Pearson or Spearman correlation. Age correlated both with the perception of severity of advanced nephropathy and the parameters of NA to chronic HD. Chronic hemodialysis (HD) treatment in end-stage renal disease (ESRD) causes important changes in the patient’s life, who is susceptible to a pathology with multiple implications in daily life and life expectancy[1]. Certain psychosocial aspects of patients on RRT are associated with worse quality of life, increased morbidity and mortality, and NA to HD7,9-11

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