Abstract
Eicosanoids are oxygenated derivatives of polyunsaturated fatty acids (PUFAs), generally of 20 carbons in chain length and often with important biological activity; the PUFAs themselves can be named according to a shorthand nomenclature describing chain length, degree of unsaturation and position of the double bond nearest the terminal methyl (“omega”) carbon. Arachidonic acid (20:4ω6) is the archetypal precursor for all main classes of the eicosanoids. Prostaglandins (PGs) A-J (ring type) are further classified as to degree of unsaturation in the side chains (eg PGE1 has one such double bond) and also according to stereochemistry; thromboxanes (A or B, according to ring type) have similar nomenclature.
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