Abstract
Nocturnal enuresis in adults is a clinical entity which has not been studied extensively. Hence data available is limited. Though less common than childhood nocturnal enuresis, it can be distressing and may denote a significant underlying pathology. It can be divided into three subgroups - persistent primary nocturnal enuresis, recurrent nocturnal enuresis and recent onset nocturnal enuresis. Persistent primary and recurrent nocturnal enuresis are commonly due to nocturnal polyuria and nocturnal detrusor overactivity. These can be treated by desmopressin with or without anticholinergic drugs. Recent onset nocturnal enuresis in adults is associated with high pressure chronic urinary retention which could cause renal impairment and even death. Therefore such patients should be evaluated to identify the underlying cause of their bladder outflow obstruction. Most of them require corrective surgery to relieve the obstruction.
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