Noble Metal Nanozymes

Abstract

Noble metal-based nanozymes have become one of the most important groups of nanozymes, especially, in the field of biomedicine due to their unique optical characteristics, chemical stability, flexible enzyme-like activity, and good biocompatibility. The catalytic mechanisms of noble-metal nanozymes that have been well analyzed. The catalytic activity of noble metal nanozymes could be adjusted by environmental factors, such as temperature and pH. The surface modification of nanozymes is also of great importance to improve the activity and selectivity of nanozyme. Integrated nanozymes could be a meaningful way to adjust the catalyst activity of noble metal nanozymes. Gold nanozyme, with stable chemical stability and significant catalase (CAT) activity, has become a key element in antitumor material design. Platinum nanozyme can also be used to remove reactive oxygen species to treat acute kidney injury. Noble metal-based nanozymes exhibit glucose oxidase, CAT, peroxidase, superoxide dismutase, and oxidase activities.