Abstract
sol and corticosteroid-binding globulin were measured in patients and controls during the short Synacthen test. Results: The basal cortisol level and basal FCI level were higher in patients (n = 65) than in healthy controls ( P < 0.001, respectively). We found that total cortisol was strongly correlated with FCI (P < 0.001) in critically ill patients; however, neither total cortisol nor FCI were associated with 30-day mortality among patients. Only severe clinical criteria (such as APACHE-III scores and low albumin) were associated with 30-day mortality. Conclusion: Our results do not suggest that FCI is more accurate than total cortisol in predicting clinical outcomes in critically ill patients. (Endocrinol Metab 26:120-125, 2011)
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