Abstract
Objective: To determine the influence of age on ileal absorption of bile acids. Design: Bile acid absorption was evaluated with the γ-emitting bile acid analogue, selenohomocholic acid taurine (SeHCAT) in 11 healthy young (aged 35 years or less) and 11 healthy elderly subjects (aged 65 years or more). Method: SeHCAT was given orally and its fractional catabolic rate (FCR) and 7-day retention were assessed by repeated external counting for the following 7 days. Fasting serum was also analysed for the lipid profile. Results: No significant difference was found between the two groups despite a significant increase in serum total and low density lipoprotein cholesterol with age. Conclusions: We could not observe any influence of age on bile acid absorption evaluated with the SeHCAT test.
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More From: European Journal of Gastroenterology & Hepatology
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