Abstract

Purpose: The presence of hippocampal sclerosis on MRI has a great impact for the treatment of patients with temporal lobe epilepsy. It influences the clinical evaluation and counselling and is considered as a key criterion for the decision to recommend epilepsy surgery in patients with temporal lobe epilepsy (TLE). However, neuropathological studies describe evidence of hippocampal sclerosis (HS) in up to 10% of non-epileptic patients, challenging the impact of MRI findings in patients with TLE. Therefore, we evaluated the prevalence of hippocampal sclerosis on MRI in the general population, using a specific protocol, sensitive for the detection of hippocampal sclerosis

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