Abstract
Cementless total knee arthroplasty (TKA) implants rely on interference fit to achieve initial stability. However, the optimal interference fit is unknown. This study investigates the effect of using different interference fit on the initial stability of tibial TKA implants. Experiments were performed on human cadaveric tibias using a low interference fit of 350 μm of a clinically established cementless porous-coated tibial implant and a high interference fit of 700 μm. The Orthoload peak loads of gait and squat were applied to the specimens with a custom-made load applicator. Micromotions and gaps opening/closing were measured at the bone-implant interface using Digital Image Correlation (DIC) in 6 regions of interest (ROIs). Two multilevel linear mixed-effect models were created with micromotions and gaps as dependent variables. The results revealed no significant differences for micromotions between the two interference fits (gait p = 0.755, squat p = 0.232), nor for gaps opening/closing (gait p = 0.474, squat p = 0.269). In contrast, significant differences were found for the ROIs in the two dependent variables (p < 0.001), where more gap closing was seen in the posterior ROIs than in the anterior ROIs during both loading configurations. This study showed that increasing the interference fit from 350 to 700 μm did not influence initial stability.
Highlights
Total knee arthroplasty (TKA) is the most common and successful surgical procedure to treat osteoarthritis (OA), offering pain relief, improvement of knee function, and providing a better quality of life for patients (Bellemans et al, 2005)
0.21 ± 0.04 implants were slightly larger compared to the low interference fit im plants (Fig. 4A), the results of the statistical model revealed no signifi cant differences between the interference fits in gait (p = 0.755) nor in squat (p = 0.232)
The comparisons of L vs anterior lateral (AL), M vs AL, posterior medial (PM) vs AL, and anterior medial (AM) vs the rest of the regions of interest (ROIs) were significant for the low interference fit implant
Summary
Total knee arthroplasty (TKA) is the most common and successful surgical procedure to treat osteoarthritis (OA), offering pain relief, improvement of knee function, and providing a better quality of life for patients (Bellemans et al, 2005). According to implant registries (Khan et al, 2016; National Joint Registry for England, Wales, 2019), younger patients have around 2.5 times higher risk of revision compared to older patients. Previous studies have shown a clear relationship between bone mineral density (BMD) and tibial component migration, where patients with higher BMD showed less migration of the tibial component (Petersen et al, 1999). This suggests that good bone quality contributes to implant fixation (Li and Nilsson, 2000)
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