Abstract
We write this note to clarify the article “Live Attenuated Influenza Vaccine Enhances Colonization of Streptococcus pneumoniae and Staphylococcus aureus in Mice” by Mina et al. (1) in order that patients or clinicians not misinterpret the study’s clinical relevance. Mina et al. described interactions between a novel live attenuated influenza virus (LAIV) strain and pathogenic bacteria at the murine respiratory mucosa. Mina et al. demonstrated that their novel attenuated virus could promote colonization of the upper respiratory tract of mice with S. pneumoniae and S. aureus but had no effect on severe bacterial disease or mortality within the lower respiratory tract. Based on that finding, the authors speculated …
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