No Association between Chronic Osteomyelitis and Parkinson?s Disease in Older People in Taiwan

Abstract

The aim of this study is to explore whether chronic osteomyelitis is associated with an increased risk of Parkinson’s disease in older people in Taiwan. By using the database from the Taiwan National Health Insurance program, this case-control study consisted of 4686 subjects aged 65 years or older with newly diagnosed Parkinson’s disease as the case group and 18744 subjects without Parkinson’s disease as the control group. After adjusting for cofounding factors, multivariable logistic regression analysis showed no association between chronic osteomyelitis and Parkinson’s disease in both gender (odds ratio = 0.71, 95% CI = 0.37-1.36 in men, and odds ratio = 0.90, 95% CI = 0.45-1.83 in women, respectively). We conclude that no association can be detected between chronic osteomyelitis and Parkinson’s disease in older people in Taiwan.