N,N′-Dibenzylethylenediamine Dipenicillin G in Turkey Erysipelas

Abstract

THE use of penicillin for the treatment of erysipelas in turkeys has been reported by several workers. Gifford and Jungherr (1946) reported recoveries of sick turkeys treated with 2 intramuscular injections of 25,000 Oxford units of penicillin at 8-hour intervals. Grey (1947) obtained good results from 4 single daily injections of 20,000 units of penicillin, in peanut oil, into the wattles. Brown et al. (1949) reported successful results by injection of 60,000 units of penicillin to each sick turkey daily for 4 days. DeLay and Koch (1950) reported that 150,000 units of penicillin in wax failed to protect turkeys against a natural infection of erysipelas, but when this was supplemented by the administration of 50,000 units of crystalline penicillin G potassium, 80 percent recovered.Recently, Glenney et al. (1952) described a new penicillin compound, N,N′-dibenzylethylenediamine dipenicillin G, which gave a blood serum-penicillin level for from 8 to 15 days from …