Abstract
Proton NMR spectroscopy was used to investigate changes in composition of lipids in the liver, kidneys and adrenal glands of Meriones unguiculatus infected with Echinococcus multilocularis. It was found that all three organs of infected animals had less total glycerophospholipid and CH 2 in the fatty acid (FA) component CHCH(CH 2CHCH) n than the corresponding organs of uninfected animals. The concentrations of other lipids in these organs were variable in their response to infection. The livers of infected jirds had lower concentrations of phosphatidylcholine (PTC), phosphatidylinositol, cholesterol (CTL) and the FA component CH 2CH 2COO, but more phosphatidylethanolamine (PTE). Kidneys of infected animals had less PTC, PTE and arachidonic acid. The adrenal glands, which were most affected by E. multilocularis infection, had lower concentrations of PTE, CTL, total FA, triacylglycerol, linoleic acid, and the FA components CH 2CH 2COO, CH 2COO, CH 2 in (CH 2) n , CHCH and CH 2CHCH.
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