Abstract
AbstractIn the reaction of 6‐chloro‐3‐methoxy‐4‐nitropyridazine 1‐oxide with methanolic ammonia and with liquid ammonia, amino‐demethoxylation occurs. By using 1H‐NMR spectroscopy we observed that with ammonia a σ‐adduct at C(5) is formed. The unusual substitution reaction at C(3) is proposed to take place in this σ‐adduct. This new substitution mechanism is discussed.
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