Abstract

E-mail: hswon@hanyang.ac.krReceived July 31, 2011, Accepted September 19, 2011Functions of the luteinizing hormone releasing hormone (LHRH) and its induced release by divalent metal ionshave received great attention because this neurotransmitter subsequently regulates the secretion of luteinizinghormone (LH). Metal-LHRH complexes were synthesized by addition of various Cu(II),Ni(II),Zn(II) ions intoLHRH in order to understand how the induced release of LHRH is possible. The degree of complexation wasmonitored by

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