Abstract
The presence of paramagnetic metal centers causes paramagnetic shift and relaxation effects on the resonances of NMR-active nuclei of ligand molecules. The origins of these shift and relaxation effects are analysed theoretically. The contact and dipolar effects, as well as the Curie spin relaxation effects, are illustrated with examples from transition metal-containing metalloproteins, and lanthanides used as extrinsic probes of proteins. In particular, structural information obtainable from lanthanide probes is critically appraised. The NMRD technique of study of nuclear paramagnetic relaxation is presented and illustrated for small Mn(II) and Gd(III) chelates useful as contrast agents for MRI.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
