NMR Spectral Studies of Some Six–Membered and Seven–Membered Saturated Heterocyclic Compound t[3]–Ethyl-r[2],c[7]-Diphenylhomopiperazin–5–One

Abstract

Some six and seven membered saturated hetero cyclic compounds were prepared. 1 H NMR were recorded in DMSO – d 6 . The chemical shifts were compared with those in CDCl 3 . The COSY, NOESY and 13 C- 1 H correlation spectra had been recorded to assign the signals unambiguously. The coupling constant of benzylic proton with one of the vicinal proton was found to be zero. The buffering effect of alkyl groups was also studied. The chemical shift values, area of the signals, multiplicity, COSY and NOESY spectra were used to assign the signals. Further COSY and NOESY and 13 C- 1 H correlation spectra were also used. The solvent effect, concentration effect, and temperature effect were also studied using DMSO- d 6 and CDCl 3 . α- effect, and polar nature of the neighbouring group were also studied.