Abstract
A N-methyl-2-pyrrolidonium hydrogensulfate [NMP][HSO4] bronsted acidic ionic liquid-promoted cyclocondensation-cyclization pathway has been established using one pot reaction of anilines, aldehydes and mercaptoacetic acid to give 4-thiazolidinone derivatives in good to promising yields using microwave irradiation. Applications for this protocol are easy workup, high yields, short reaction times, variability of functional groups, recyclability and solvent-free conditions.
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