Abstract

 CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
 The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
 This review assesses nivolumab (Opdivo) for injection, IV infusion, 10 mg nivolumab/mL, 40 mg and 100 mg single-use vials.
 Indication: Opdivo in combination with fluoropyrimidine- and platinum-containing chemotherapy, for the treatment of adult patients with human epidermal growth factor receptor 2-negative advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma.
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