Abstract

The role of nitrosative stress and its products in pathological processes in the brain is reviewed. The interactions of nitric oxide and its intermediates with biomolecules under physiological conditions and neurodegenerative pathologies associated with nitrosative stress are discussed. Data on the modulation of protein functions after their covalent modifications with reactive nitrogen species are presented. We discuss the response of the immune system to nitrotyrosine-containing proteins and a possible role of nitrotyrosine as a marker of nitrosative stress in the brain.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.