Nitrogen-Containing Graphene for Electrochemical Sensing of Glucose

Abstract

N-containing graphene was an excellent candidate for sensing and biosensing because of its comparable atomic radius with that of carbon and the formation of strong bonds. Its presence influenced the atomic charge distribution on the graphene scaffold, thereby enhancing the electrochemical activity. Here, nitrogen-containing graphene (N-graphene) prepared from papaya seeds was used to fabricate the electrode for the electrochemical oxidation of glucose using cyclic voltammetry and amperometry studies. The fabricated electrode showed a good response (6s) towards electrochemical oxidation of glucose with a linear range of 50-800 mg/L (R2=0.99369), the sensitivity of ~ 10.888 μAM−1cm−2 along with a detection limit of 0.9 μM. It efficiently determined the glucose concentration in three real samples (apple juice, coco-cola, and honey), which were found to be 2.06%, 4.21%, and 41%, respectively. Moreover, the electrode exhibited an acceptable reproducibility (RSD 7.6%), and the stability was observed as 82..6% of the initial value up to 15 days.