Abstract
A 78 year-old lady who received nitrofurantoin for two years developed chronic active hepatitis. In spite of withdrawal of Nitrofurantoin her condition continued to deteriorate, and a liver biopsy revealed severe chronic active hepatitis. She was treated by prednisone which resulted in improvement in her liver function tests and her general condition. However, two months later the patient developed a relapse of severe hepatitis with hepatic failure and she died in spite of treatment.
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