Abstract
NBT reduction test was performed in 121 pregnant women, 40 postpartum women, and 97 nonpregnant women of childbearing age. In the first and third trimesters the percentage of NBT positive cells was within the normal limits. During the weeks 14 to 27 (second trimester) of pregnancy there was a significant increase (P < 0.005) in NBT reduction, with a peak during weeks 18 to 24 (fifth and sixth months). Twenty-four hours after delivery we found a second rise and two days later the values returned to normal. It has been suggested that the increase in NBT reduction during pregnancy and 24 hours after delivery is in correlation with the penetration of trophoblasts in the maternal circulation which takes place at the same time. We conclude that the NBT reduction test cannot serve as an aid to the differentiation between bacterial and viral infection in the second trimester of pregnancy.
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