Abstract
The nitro musks - musk xylene, musk ketone, musk ambrette, musk moskene and musk tibetene - which are extensively utilized as fragrances in cosmetics and detergents, were determined in a total of 32 human adipose tissue samples and 23 human milk samples from northern Germany. The residue levels ranged from 0.02 to 0.22 mg musk xylene/kg fat and from 0.01 to 0.09 mg musk ketone/kg fat, respectively (1 fat sample contained 0.22 mg musk ketone/kg fat). In a few samples musk ambrette and musk moskene were detected at low levels. Musk tibetene could not be detected at all. Apart from alimentary intake, the dermal sorption of these compounds from cosmetics and detergents is discussed as possible contamination routes.
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