Abstract

AbstractNitric oxide (NO) is a ubiquitous messenger molecule with multiple roles in cellular physiology and signaling. Recent studies have indicated the role of NO as an inflammatory mediator and as a potential non invasive biomarker. The current review focuses on the role of nitric oxide and its derivatives including nitrites as potential non invasive biomarkers for assessing airway inflammation in respiratory disorders including asthma, bronchiectasis, cystic fibrosis and chronic obstructive pulmonary disease.

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