Nirvanol treatment of chorea

Abstract

<h2>Summary</h2> Six children varying in age from seven to twelve years were treated with nirvanol. In every case some sign of nirvanol sickness was obtained. Total dosage varied from 2.4 gm. to 9.4 gm. Three patients who did not promptly develop the signs were then given larger doses. In no case was improvement noted after administration of the drug. Three children were treated after an interval of time with intravenous injections of dead typhoid bacilli. In two of these cases prompt and spectacular improvement occurred.