NIRS-Based Muscle Oxygenation Is Not Suitable to Compute Convective and Diffusive Components of O 2 Transport at V̇O 2max.

Abstract

1Department of Molecular Medicine, University of Pavia, Pavia, ITALY 2Institute of Biomedical Technologies, National Research Council, Milan, ITALY 3Department of Medicine, University of Udine, Udine, ITALY 4Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA Address for Correspondence: Simone Porcelli, MD, PhD, Assistant Professor in Human Physiology Institute of Physiology, Department of Molecular Medicine University of Pavia, Italy, Via Forlanini 6, 27100 Pavia – Italy; Phone: +39 0382987538; E-mail: [email protected] Conflict of Interest and Funding Source: The authors have no conflicts of interest to disclose. Harry Rossiter is supported by grants from NIH (R01HL151452, R01HL153460, P50HD098593, R01DK122767, P2CHD086851) and the Tobacco Related Disease Research Program (T31IP1666). He reports consulting fees from Omniox Inc., and is involved in contracted clinical research with Boehringer Ingelheim, GlaxoSmithKline, Novartis, AstraZeneca, Astellas, United Therapeutics, Genentech and Regeneron. He is a visiting Professor at the University of Leeds, UK. The views of the perspective are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation. This perspective does not constitute endorsement by the American College of Sports Medicine.