Abstract
Females of Nippostrongylus brasiliensis produced little pheromone and males were essentially unresponsive to the female pheromone until after the final larval molt at about 5 days after infection in mice. After the fifth day, female pheromone production decreased steadily with increasing age, possibly as a result of host immune reaction. Male responsiveness remained high from the fifth day through the ninth day, then their response diminished. Females at various ages ranging from 4 to 13 days after infection responded at low levels to pheromone produced by males of the same age. No time of day influence was found within the 24-hr cycle on male or female production of pheromone or response to the opposite sex's pheromone.
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