Nipple Paget's Disease Revealing a CIS and an Underlying Infiltrating Carcinoma about a Case and Review of the Literature

Abstract

We report in this article the case of a patient treated for nipple Paget's disease and in whom clinical and radiological investigations found the association of Paget with carcinoma in situ and infiltrating carcinoma of the breast. Paget's disease of the nipple is a rare variant of CIS. It is associated with an underlying breast adenocarcinoma in more than 80% of cases. Its research must be systematic in imaging, namely MRI. The management of Paget's disease depends on whether or not it is associated with carcinoma in situ or invasive carcinoma. Through our case and in the light of the review of the literature, we insist on the particularity of the positive and differential diagnosis of this entity as well as the therapeutic side, the good knowledge of which allows practitioners to make the diagnosis in time and therefore to improve the prognosis of these young patients.