Abstract
Niosomes are a non-ionic spherical surfactant that is biodegradable, non-toxic, more durable, and cost effective as compare to liposomes. Through niosomes delivery of both hydrophilic and liophilic drug can be achieve very constructively. To achieve targeted drug delivery, drug binds to receptor site and then we can get the therapeutic action without attaching to other sites to prevent the undesirable or side effect of active pharmaceutical ingredient to the systemic circulation, hence niosomes is a very novel drug delivery system by which we can achieve very safe drug delivery at the site of action needed with high efficacy. In this review paper we try to compile all the information related with niosomes like introduction, structure, composition advantages, types, disadvantage, preparation methods, factor affecting, evaluation studies, applications of niosomes, difference between liposomes and niosomes, current available marketed formulation and patents, final conclusion and at last future perspective of niosomes.
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