Niosomal Drug Delivery for Oral Route

Abstract

Abstract: Niosomes are artificial vesicles with potential technological advantages. They are non-ionic surfactant vesicles. As efficient drug delivery systems with a wide range of uses, niosomes have the same potential benefits as phospholipid vesicles (liposomes), including the capacity to hold both water- and lipid-soluble pharmaceutical molecules. Niosomes can also be thought of as more cost-effective, chemically stable, and occasionally physically stable alternatives to liposomes. Simple preparation techniques and commonly used surfactants in pharmaceutical technology can be employed to create niosomes. Numerous studies have covered noisome physicochemical characteristics and their uses as drug delivery vehicles. In this report, a brief and simplified summary of different theories of self-assembly are discussed. Furthermore, manufacturing methods, physical characterization techniques, bilayer membrane additives, unconventional niosomes (discomes, proniosomes, elastic and polyhedral niosomes), their recent applications as drug delivery systems, limitations and directions for future research will be discussed.