Abstract

This article summarizes the newest knowledge related to effect of light on circadian regulation. There are several models each of which shows an action spectrum for light-induced melatonin suppression. However, these models are insufficient to calculate the combined effects of the intrinsically photosensitive retinal ganglion cells (ipRGC), rods and cones on melatonin suppression. Also in common environment, not monochromatic light sources but polychromatic light sources are used. Non-visual responses to a polychromatic light source may be different to that predicted from these models derived from the experiments using monochromatic light. At present, it can be recommended that high color temperature lighting at night should be avoided, especially for children.

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