Abstract

This objective of this policy opinion article was to address a perspective if chrono-eating can help prevent immunodeficiency diseases by optimizing circadian rhythms of nutrient assimilation and metabolism. In the modern era, eating timing, sequence, and frequency have been modified significantly. People tend to consume fast foods during later times of the circadian phase or almost 24-h period. Rising evidence indicates that eating at wrong times (i.e., evening and night) and inadequate physical activity would lead to suboptimal physiological rhythms of nutrient assimilation and metabolism. This trend is postulated to weaken immunity and cause obesity, diabetes, and other immunodeficiency and autoimmune diseases. These abnormalities are amongst the foremost metabolic disorders worldwide. Eating slowly releasing energy later in the evening and overnight may help optimize immunity. Therefore, chrono-eating is a mounting science that helps optimize circadian food consumption behavior to prevent, or at the very least, reduce immunodeficiency and associated metabolic disorders development.

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