Nicotinic acid‐supported cobalt ferrite‐catalyzed one‐pot synthesis of substituted chromeno[3,4‐b]quinolines

Abstract

One‐pot synthesis of substituted chromeno[3,4‐b]quinoline derivatives was developed by three‐component reaction of aldehydes, dimedone or 1,3‐cyclohexadione, and 4‐aminocoumarin in the presence of nicotinic acid‐supported cobalt ferrite [CoFe2O4@SiO2@Si(CH2)3Cl@NA] as a novel magnetic catalyst in chloroform at reflux conditions. Nicotinic acid‐supported cobalt ferrite was characterized via Fourier transform infrared spectroscopy, X‐ray diffraction, thermal gravimetric analysis, scanning electron microscopy, high‐resolution transmission electron microscopy, energy‐dispersive X‐ray spectroscopy, and vibrating sample magnetometry. Moreover, the catalyst could be easily recovered by magnetic separation and recycled up to five times without significant loss of its catalytic activity. The products formed in excellent yields over appropriate reaction times under environmentally friendly conditions. High efficiency and easy isolation of the catalyst from products by simple magnetic attraction are some of the considerable advantages of this procedure.