Abstract
# {#article-title-2} Writ e Click correspondence this week includes an instructive exchange between author, commenter, and biostatistician regarding the need to control for type I error. In reference to the recent article by Newhouse et al., “Nicotine treatment of mild cognitive impairment: A 6-month double-blind pilot clinical trial,” Dr. Gold warns of the possibility of type I error in the article's secondary outcomes analyses and against reading too much into the significant p values reported. The authors agree that, as an exploratory study, type I error was not controlled for as multivariate analysis would have been impractical. Our own …
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