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Abstract
Nicotinic acetylcholine receptors have been suggested to participate in morphogenetic processes during development of the nervous system. In this study, nicotine applied both in ovo and in vitro produced a reduction of the neuritic length of cholinoceptive neurons of the developing chick tectum, whereas α-bungarotoxin produced the opposite effect. Taken together with previous data, our results are indicative of a role of the α-bungarotoxin-sensitive nicotinic receptors in neural development.
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