NiCoMnS/rGO nanocomposite for enzyme-free and ultrasensitive electrochemical catalysis of hydrogen peroxide and glucose

Abstract

It is attractive to develop non-noble-metal nanomaterials with large surface area and good conductivity as a high-active catalyst electrode for molecular detection in electrochemical sensors. In this work, we successfully fabricated NiCoMnS/rGO by one-step hydrothermal method, which showed good peroxidase-like activity in an acidic environment. The NiCoMnS/rGO modified electrode exhibited excellent enzyme-free electrochemical catalysis performance for hydrogen peroxide (H2O2) reduction in acidic solutions and glucose oxidation in alkaline solutions. For the detection of H2O2, this electrochemical sensor displayed a wide linear range from 10.0 μM to 7.5 mM with a low limit of detection of 1.1 μM. As for glucose, it also showed a wide linear range from 50.0 μM to 1.3 mM with a low limit of detection of 1.0 μM. Moreover, it had good stability and reproducibility. It was also used for the determination of H2O2 and glucose in real samples. This nanomaterial held great promise as an enzyme-free sensing platform toward H2O2 and glucose detection.