Abstract
Levofloxacin is an antibiotic used to treat bacterial infections. This work aimed to produce a new modified electrode for the determination of levofloxacin. The graphene nanoribbons (GNRs) were prepared by chemical oxidation and a layered double hydroxide (LDH) containing nickel and cobalt cations (Ni/Co–LDH) using electrodeposition. The oxidation peak current of levofloxacin showed an increase and shifted to lower potentials using a glassy carbon electrode modified with GNRs and Ni/Co–LDH. The reported electrode demonstrated a linear dynamic range from 5.0 to 150.0 μmol L−1 with a limit of detection for levofloxacin of 1.1 μmol L−1. The modified electrodes were successfully utilized for the determination of levofloxacin in urine.
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