Abstract
A nickel-catalyzed cross-electrophile coupling of unactivated (hetero)aryl sulfones with aryl bromides via CS bond activation at ambient temperature is developed. By relying on the use of nickel as catalyst, 2,2′-bipyridine (bpy) as ligand, magnesium turnings as mediator, and THF as solvent, a myriad of biaryls could be facilely prepared in moderate to good yields with reasonable functionality compatibility. The present method potentially serves as an attractive alternative to conventional methods, for the use of unreadily available, relatively expensive, and sensitive organometallic reagents could be avoided.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
