Abstract

Two novel coordination complexes, namely, [Ni2(TPT)2(H2O)2] (1) and [Co(TPT)(H2O)2]n (2), based on the 3-(tetrazol-5-yl)-5-(pyrid-2-yl)-1,2,4-triazole ligand were produced by solvothermal synthesis. Magnetic studies showed that between adjacent metal ions, anti-ferromagnetic coupling existed in complexes 1 and 2. The complexes’ application values against catecholamine vasoactive drug-induced acute pancreatitis complicated with abdominal infection was discussed. Subsequently, the mechanism was investigated. ELISA analysis was initially used to identify the inflammatory-response levels in acute pancreatitis complicated with abdominal infection after treatment with the complex. Additionally, the C-reactive protein content of plasma was tested through the immuno-projection turbidimetric approach.

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