Abstract
Nickel has been shown to be related to a wide variety of pathophysiological conditions spanning a broad spectrum of events from gamete formation to the attainment of sexual maturity. There is, however, little, if any data available in regard to nickel toxicity in animals of different ages and sex. The purpose of this study was to determine the time course and extent of nickel-induced lethality in juvenile male and female mice and to compare juvenile responses to those in adult mice of both sexes.
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