Abstract
The function of glycosphingolipids on cell surface membranes as “cellular” antigen has recently received much attention. Hanganutziu-Deicher (HD) antigen is an antigen recognized by a human heterophile antibody, HD antibody. Glycosphingolipids containing N-glycolylneuraminic acid (NeuGc) were found to possess HD antigen activity (1). NeuGc is widely distributed in most animals except human and chickens. Recently, the antigen has been found in malignant tissues and sera from patients with various tumors (2, 3). Here we described isolation and characterization of HD antigen-active gangliosides as a tumor associated antigen in human colon carcinoma and melanoma tissues.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
