Abstract

The 2016 World Health Organization (WHO) classification of central nervous system (CNS) tumours heralded a shift towards an integrated diagnosis for brain tumours, incorporating both histological features and molecular data.1 This was re-iterated in 2018 by the Consortium to Inform Molecular and Practical Approaches to CNS Tumour Taxonomy (c-IMPACT).2 It is now recognised that a tumour's molecular phenotype not only assists in classification, but also provides prognostic information and impacts clinical management.

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