Abstract

Montelukast sodium is well known pharmaceutically for its action as leukotriene antagonist and reliving symptoms associated with asthma is available in the market as tablet, chewable tablet, and powder. The aim of this study was to develop newly simple selective ultraviolet spectrophotometry (UV) method for daily routine analysis of quality control department. The UV method was developed with wavelength at 287.0 nm. This newly developed method was effectively applied to tablet dosage form of the motelukast sodium follow the Beer’s Lamberts at range 2.5–50 μg/mL. The validated parameters were carryout such as linearity, accuracy, precision, and specificity. The result of validation statistically studied and found to be satisfactory.

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