Abstract
We describe an uncommon presentation of a rare disease in a 15-day-old term infant with a sudden increase in head circumference, wide sutures, and open fontanels. Magnetic resonance imaging/magnetic resonance venography showed cerebral venous sinus thrombosis (CVST). The infant had multiple maternal-fetal risk factors for CSVT, with screening coagulation studies within normal limits. Unfractionated heparin was the treatment of choice with a suitable response and no further thrombosis or hemorrhages. Neurologic examination findings on discharge and at 2 months were within normal limits.
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